Haemostatic resuscitation

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Haemostatic resuscitation.

Recommendations for resuscitation of patients in early haemorrhagic shock, with active ongoing bleeding, have evolved in recent years. This review covers current theories of the pathophysiology of shock and recommended treatments, including damage control surgery, deliberate hypotensive management, administration of antifibrinolytics, early support of the coagulation system, and the possible ro...

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Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!

The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association with modern trauma care is poorly described. In addition, early predictors of massive transfusion, ...

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Effect of Haemostatic Control Resuscitation on mortality in massively bleeding patients: a before and after study

BACKGROUND AND OBJECTIVES Evidence supporting the use of platelets and plasma in resuscitation of massive bleedings is questionable. Current consensus guidelines recommend restrictive use. Our aim was to determine the effect of changing the transfusion practice on 30-day survival in massively bleeding patients. MATERIALS AND METHODS Consecutive adult patients receiving more than 10 units of r...

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Prolonged elevations in haemostatic

There is a marked socioeconomic gradient in the incidence of coronary heart disease (CHD) and in subclinical atherosclerosis (1, 2). Haemostatic and rheological factors may contribute to this pattern. Socioeconomic gradients in fibrinogen have been described in the Whitehall II study (3) and in other cohorts (4, 5). Socioeconomic status (SES) is also inversely associated with the concentration ...

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The Ideal Haemostatic Dressing

Email: [email protected] Introduction The problem of haemorrhage is well recognised by the deploying military medical community. In 1970 Maughon, after examining the combat deaths of 2600 American servicemen in Vietnam, articulated the simple requirement that more be done on the battlefield to prevent death from haemorrhage: “The striking feature was to see healthy young Americans with a...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2012

ISSN: 0007-0912

DOI: 10.1093/bja/aes389